Sepsis-induced cholestasis
نویسندگان
چکیده
منابع مشابه
REVIEW Sepsis-Induced Cholestasis
Jaundice and hepatic dysfunction frequently accompany a variety of bacterial infections. The relationship between sepsis and jaundice, particularly in a pediatric population, was reported as early as 1837.1 Jaundice may result either directly from bacterial products or as a consequence of the host’s response to infection. Frequently, both factors contribute to the development of jaundice. In ad...
متن کاملSepsis and cholestasis.
24 Notter RH, Smith S, Taubold RD, Finkelstein JN. Path dependence of adsorption behavior of mixtures containing dipalmitoyl phosphatidyl choline. Pediatr Res 1982;16:515-9. 25 Notter RH, Shapiro DL. Lung surfactant in an era of replacement therapy. Pediatrics 1981 ;68:781-9. 26 Enhorning G, Roberton B, Milne E, Wagner R. Radiological evaluation of the premature newborn rabbit after pharyngeal ...
متن کاملDrug-induced cholestasis: case report
Background: Clopidogrel is an effective anti-platelet drug that is commonly prescribed for patients with atherosclerotic coronary and peripheral vascular diseases, especially after angioplasty and coronary artery bypass graft surgery. Even though this drug seems safe, there are case reports of important side effects with its use. Case Presentation: The patient was 67 years old male admitted wi...
متن کاملThe molecular pathogenesis of cholestasis in sepsis.
Sepsis-induced cholestasis is a complication of infection. Infections cause systemic and intrahepatic increase in proinflammatory cytokines which result in impaired bile flow ie. cholestasis. Several other mediators of impairment in bile flow have been identified under conditions of sepsis such as increased nitric oxide production and decreased aquaporin channels. The development of cholestasis...
متن کاملDrug‐induced cholestasis
Cholestatic drug-induced liver injury (DILI) can be a diagnostic challenge due to a large differential diagnosis, variability in clinical presentation, and lack of serologic biomarkers associated with this condition. The clinical presentation of drug-induced cholestasis includes bland cholestasis, cholestatic hepatitis, secondary sclerosing cholangitis, and vanishing bile duct syndrome. The ass...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2007
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.21676